Effect of Natural Hirudin on Random Pattern Skin Flap Survival in a Porcine Model
نویسندگان
چکیده
منابع مشابه
The Effect of Enoxaparin and Clopidogrel on Survival of Random Skin Flap in Rat Animal Model
BACKGROUND Necrosis of skin flaps is considered as an important complication in reconstructive surgery. We conducted an experimental study to investigate the efficacy of low-molecular weight heparin, clopidogrel and their combination to improve the flap survival. METHODS Forty male, adult Sprague-Dawlay rats were divided randomly into 4 groups. Standard rectangular, distally based dorsal ran...
متن کاملOral administration of alanyl-glutamine and glutamine improve random pattern dorsal skin flap survival in rats
Objective(s): Skin flap necrosis is the most common postoperative side effect in reconstructive surgeries. Glutamine (GLN) has been shown to accelerate wound healing process. The purpose of this study was to evaluate the effects of GLN either in free form or in the dipeptide form along with L- alanyl (Ala-GLN) on random skin flaps survival in rats.Materials and Methods: Dorsal skin flaps with c...
متن کاملthe effect of enoxaparin and clopidogrel on survival of random skin flap in rat animal model
background necrosis of skin flaps is considered as an important complication in reconstructive surgery. we conducted an experimental study to investigate the efficacy of low-molecular weight heparin, clopidogrel and their combination to improve the flap survival. methods forty male, adult sprague-dawlay rats were divided randomly into 4 groups. standard rectangular, distally based dorsal random...
متن کاملFavorable effects of progesterone on skin random flap survival in rats
Objective(s): The aim of this study is to determine the effects of progesterone treatment on the survival of random skin flaps. Materials and Methods: McFarlane flaps were established and 40 male rats were randomly assigned to the progesterone-treated as the test group or normal saline-treated as the control group. Progesterone or normal saline (10 mg/kg) was administered intraperitoneally onc...
متن کاملEffect of Systemic Antioxidant Allopurinol Therapy on Skin Flap Survival
BACKGROUND It has been reported that systemic administration of allopurinol improves cell survival. This study was aimed to evaluate effects of allopurinol on skin flaps in dogs. METHODS Twenty dogs underwent one skin flap surgery with a 2-week interval. The first procedure was performed according to the standard protocols. The second phase was started by a 1-week pretreatment with all...
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ژورنال
عنوان ژورنال: Journal of International Medical Research
سال: 2012
ISSN: 0300-0605,1473-2300
DOI: 10.1177/030006051204000624